Improving Mortality in Subclinical Acute Kidney Injury After Cardiac Surgery by Composite Biomarker Panel

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Cardiac biomarkers and acute kidney injury after cardiac surgery.

OBJECTIVES To examine the relationship of cardiac biomarkers with postoperative acute kidney injury (AKI) among pediatric patients undergoing cardiac surgery. METHODS Data from TRIBE-AKI, a prospective study of children undergoing cardiac surgery, were used to examine the association of cardiac biomarkers (N-type pro-B-type natriuretic peptide, creatine kinase-MB [CK-MB], heart-type fatty aci...

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Improving the Prediction of Cardiac Surgery–Associated Acute Kidney Injury

Introduction Acute kidney injury (AKI) is a potentially fatal complication of cardiac surgery. The inability to predict cardiac surgery-associated AKI is a major barrier to prevention and early treatment. Current clinical risk models for the prediction of cardiac surgery-associated AKI are insufficient, particularly in patients with preexisting kidney dysfunction. Methods To identify intraope...

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Acute kidney injury in septua- and octogenarians after cardiac surgery

BACKGROUND An increasing number of septua- and octogenarians undergo cardiac surgery. Acute kidney injury (AKI) still is a frequent complication after surgery. We examined the incidence of AKI and its impact on 30-day mortality. METHODS A retrospective study between 01/2006 and 08/2009 with 299 octogenarians, who were matched for gender and surgical procedure to 299 septuagenarians at a unive...

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Mortality prediction in patients with acute kidney injury requiring renal replacement therapy after cardiac surgery.

BACKGROUND AND OBJECTIVE Acute kidney injury (AKI) is a common and potentially serious postoperative complication after cardiac surgery, and it remains a cause of major morbidity and mortality. The aim of our study was to assess the prognostic illness severity score and to estimate the significant risk factors for poor outcome of patients with AKI requiring renal replacement therapy (RRT) after...

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Acute kidney injury in cardiac surgery

Purpose of review Acute kidney injury (AKI) is a long-recognized complication of cardiac surgery. It is a commonly encountered clinical syndrome that, in its most severe form, increases the odds of operative mortality three to eight-fold. The pathogenesis of cardiac surgery-associated acute kidney injury (CSA-AKI) is complex. No single intervention is likely to provide a panacea, and thus, the ...

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ژورنال

عنوان ژورنال: The Annals of Thoracic Surgery

سال: 2018

ISSN: 0003-4975

DOI: 10.1016/j.athoracsur.2018.06.027